Ukusetyenziswa kwee-organic acids kunokuphucula ukusebenza kokukhula kweenkukhu ezikhulayo kunye neehagu. UPaulicks et al. (1996) benze uvavanyo lwe-dose titration ukuvavanya isiphumo sokunyusa amanqanaba e-potassium dicarboxylate ekusebenzeni kweehagu ezikhulayo. 0, 0.4, 0.8, 1.2, 1.6, 2.0, 2.4 kunye ne-2.8%i-potassium dicarboxylatezongezwa kwisondlo sokuqala samantshontsho eehagu atya isoya yombona. Umyinge wokwanda kwemihla ngemihla, ukutya kwemihla ngemihla kunye nezinga lokuguqulwa kokutya kweqela le-potassium dicarboxylate zonyuswe nge-13%, 9% kunye ne-4% ngokulandelelana. Xa kuthelekiswa neqela elinganyangwanga, ukongeza i-2% PD yonyuse ubunzima bomzimba nge-22%. Ngokwenqanaba eliphezulu lokongeza elibhaliswe ziigunya zaseYurophu le-1.8%, ukutyeba kunokwandiswa ukuya kwi-14%. Ukuthathwa kokutya konyuswe ngedosi efanayo. Izinga lokuguqulwa kokutya (FCR) lehle ngokuthe ngqo ngokonyuka kwe-PD, ukusuka kwi-1.59 ukuya kwi-1.47. Abanye abaphandi bahlolisise impembelelo ye-PD ekusebenzeni kwamantshontsho eehagu. Itheyibhile 1 ishwankathela iziphumo zovavanyo zeziphumo ze-PD ekutyebeni (WG) kunye ne-FCR.

Iziphumo ze-potassium dicarboxylate ekuzuzeni ubunzima bezilwanyana kunye nokuguqulwa kokutya

I-Potassium dicarboxylateibhalisiwe njengesixhobo sokukhulisa iintsholongwane esingesiso isibulali-ntsholongwane, esijolise ekuthatheni indawo yee-antibiotics ekutyeni nasekuqinisekiseni ukufikelela kwabathengi kwiimveliso ezikhuselekileyo. Ke ngoko, iingenelo zokusebenzisa i-potassium dicarboxylate kufuneka zithelekiswe nemiphumo yokusetyenziswa rhoqo kwee-antibiotics zokutya. I-Tylosin yenye yee-antibiotics zokutya ezisetyenziswa rhoqo kwiihagu. UDanielsen (1998) uthelekise ukusebenza kokukhula kweehagu ezinyangwa nge-antibiotic growth promoter tylosin okanye i-PD. Iziphumo zibonise ukuba i-potassium dicarboxylate ingathatha indawo yee-antibiotics zokutya ngaphandle kwempembelelo embi ekusebenzeni kwezilwanyana. Izifundo zibonise ukuba i-potassium dicarboxylate iphucula ukusebenza kokukhula kwezilwanyana, kwaye ukusebenza kwee-antibacterial kwe-potassium dicarboxylate yeyona nto iphambili echaphazela ukusebenza kokukhula.

Impembelelo yee-organic acids ekusebenzeni kokukhula ayinxulunyaniswanga nje kuphela nempembelelo embi yee-organic acids kwiintsholongwane, kodwa ikwanokunciphisa i-pH yamathumbu. Ukongeza, ii-ions ezingalunganga ze-asidi zinempembelelo entle kwi-symbiosis yezityalo zamathumbu. Zonke ezi ziphumo zinciphisa imetabolism ephakathi kwaye zinceda ekuphuculeni ukusebenza kokukhula. Ukuphuculwa kokusetyenziswa kwezondlo kungenxa yokunciphisa ukhuphiswano lwee-microbial kwizondlo, kodwa kukwangumphumo wokugaya izondlo nge-enzyme esebenzayo. URoth et al. (1998) baxele ukuba i-1.8% ye-PD supplementation iphucule ukugaywa, ikakhulu ibonisa utshintsho lomsebenzi we-intestinal microbiota. Ekubeni malunga ne-80% ye-nitrogen kwindle ivela kwiintsholongwane, iziphumo zabo zibonisa ukuba ukongezwa kwe-PD kunokunciphisa inani lezondlo ezinokubila ezingena kwi-hindgut ngokuphucula ukugaywa kwe-enzyme yamathumbu amancinci. Bakwacebisa ukuba inokuphucula imeko ye-carcass ngokwenza kube lula ukufaka ii-amino acids emzimbeni. I-Partanene kunye noMroz (1999) babonise ukuba imithombo yeproteni ekumgangatho ophantsi inempembelelo enkulu ekuphuculeni ukugaywa kweproteni kunemithombo yeproteni esemgangathweni ophezulu.

I-potassium dicarboxylate inokuphucula ukutyeba kwezilwanyana, ukutya ukutya kunye nokuguqulwa kokutya. Ukuphuculwa kokusebenza kokukhula kuyafana noko kukhuthazwa kukukhula. Ke ngoko, i-potassium dicarboxylate iye yaba yindawo esebenzayo yokutshintsha ii-antibiotics zokutya ngenxa yeempawu zayo ezintle. Impembelelo kwi-microflora ithathwa njengeyona ndlela iphambili yokusebenza, kwaye akukho mngcipheko wokuxhathisa iintsholongwane. Inciphisa izinga lokwanda kwe-E. coli kunye ne-Salmonella kwiimveliso zenyama.