2. I-Glyceryl butyrate

I-asidi ye-butyric inevumba elibi kwaye kulula ukuyitshintsha, kwaye kunzima ukufikelela ngasemva kwamathumbu ukuze idlale indima emva kokutyiwa zizilwanyana, ngoko ke ayinakusetyenziswa ngokuthe ngqo kwimveliso. I-Glyceryl butyrate yimveliso enamafutha ye-asidi ye-butyric kunye ne-glycerin. I-asidi ye-butyric kunye ne-glycerin zibotshelelwe zii-covalent bonds. Zizinzile ukusuka kwi-pH1-7 ukuya kwi-230 ℃. Emva kokutyiwa zizilwanyana, i-glyceryl butyrate ayiboli esiswini, kodwa iyabola ibe yi-asidi ye-butyric kunye ne-glycerin emathunjini phantsi kwesenzo se-pancreatic lipase, ikhupha kancinci i-asidi ye-butyric. I-Glyceryl butyrate, njengesongezelelo sokondla, kulula ukuyisebenzisa, ikhuselekile, ayinatyhefu, kwaye inencasa ekhethekileyo. Ayisombululi nje kuphela ingxaki yokuba i-asidi ye-butyric kunzima ukuyongeza njengolwelo kwaye ivumba kakubi, kodwa ikwaphucula ingxaki yokuba i-asidi ye-butyric kunzima ukuyifikelela kwindlela yamathumbu xa isetyenziswa ngokuthe ngqo. Ithathwa njengenye yezona zinto zibalaseleyo eziphuma kwi-butyric acid kunye neemveliso ze-antihistamine.

2.1 I-Glyceryl Tributyrate kunye ne-Glyceryl Monobutyrate

I-TributyrinIqulethe iimolekyuli ezi-3 ze-butyric acid kunye nemolekyuli e-1 ye-glycerol. I-Tributyrin ikhupha kancinci i-butyric acid emathunjini nge-pancreatic lipase, inxalenye yayo ikhutshwa ngaphambili emathunjini, kwaye inxalenye yayo inokufikelela ngasemva emathunjini ukuze idlale indima; I-monobutyric acid glyceride yenziwa yimolekyuli enye ye-butyric acid ebopha kwindawo yokuqala ye-glycerol (indawo ye-Sn-1), eneempawu ze-hydrophilic kunye ne-lipophilic. Ingafikelela ngasemva emathunjini kunye nejusi yokugaya ukutya. I-butyric acid ethile ikhutshwa yi-pancreatic lipase, kwaye enye ifunxwa ngokuthe ngqo ziiseli ze-epithelial zamathumbu. Ibola ibe yi-butyric acid kunye ne-glycerol kwiiseli ze-mucosal zamathumbu, ikhuthaza ukukhula kwe-intestinal villi. I-Glyceryl butyrate ine-molecular polarity kunye ne-nonpolarity, enokungena ngempumelelo kwi-hydrophilic okanye i-lipophilic cell wall membrane yebhaktheriya ephambili ye-pathogenic, ihlasele iiseli zebhaktheriya, itshabalalise isakhiwo seseli, kwaye ibulale iibhaktheriya eziyingozi. I-monobutyric acid glyceride inefuthe elinamandla lokulwa neentsholongwane kwiintsholongwane ezinegram kunye neentsholongwane ezinegram, kwaye inefuthe elingcono lokulwa neentsholongwane.

2.2 Ukusetyenziswa kwe-glyceryl butyrate kwiimveliso zasemanzini

I-Glyceryl butyrate, njenge-derivative ye-butyric acid, inokukhupha i-butyric acid ngempumelelo phantsi kwesenzo se-pancreatic lipase yamathumbu, kwaye ayinavumba, izinzile, ikhuselekile kwaye ayinantsalela. Yenye yezona ndlela zibalaseleyo zokusebenzisa amayeza okubulala iintsholongwane kwaye isetyenziswa kakhulu kwi-aquaculture. UZhai Qiuling et al. babonise ukuba xa i-100-150 mg/kg tributylglycerol ester yongezwa kwisondlo, izinga lokutyeba, izinga lokukhula elithile, imisebenzi yee-enzymes ezahlukeneyo zokugaya ukutya kunye nokuphakama kwe-intestinal villi ngaphambi nasemva kokongezwa kwe-100 mg/kg tributylglycerol ester kunokwandiswa kakhulu; UTang Qifeng kunye nabanye abaphandi bafumanise ukuba ukongeza i-1.5g/kg tributylglycerol ester kwisondlo kunokuphucula kakhulu ukusebenza kokukhula kwePenaeus vannamei, kwaye kunciphise kakhulu inani le-pathogenic vibrio emathunjini; UJiang Yingying et al. kufumaniseke ukuba ukongeza i-1g/kg ye-tributyl glyceride kwisondlo kunokunyusa kakhulu izinga lokutyeba kwe-Allogynogenetic crucian carp, kunciphise i-feed coefficient, kwaye kwandise umsebenzi we-superoxide dismutase (SOD) kwi-hepatopancreas; Ezinye izifundo zibonise ukuba ukongezwa kwe-1000 mg/kgi-tributyl glycerideUkutya okunokunyusa kakhulu umsebenzi we-intestinal superoxide dismutase (SOD) weJian carp.