Kangangeminyaka emininzi i-butyric acid ibisetyenziswa kwishishini lokutya ukuphucula impilo yamathumbu kunye nokusebenza kwezilwanyana. Izizukulwana ezintsha ezininzi ziye zaziswa ukuphucula ukuphathwa kwemveliso kunye nokusebenza kwayo ukusukela oko kwenziwa uvavanyo lokuqala ngeminyaka yoo-1980.

Kangangeminyaka emininzi i-butyric acid ibisetyenziswa kwishishini lokutya ukuphucula impilo yamathumbu kunye nokusebenza kwezilwanyana. Izizukulwana ezintsha ezininzi ziye zaziswa ukuphucula ukuphathwa kwemveliso kunye nokusebenza kwayo ukusukela oko kwenziwa uvavanyo lokuqala ngeminyaka yoo-1980..

1. Uphuhliso lwe-butyric acid njengesongezelelo sesondlo

Kwiminyaka yoo-1980 > I-Butyric Acid esetyenziselwa ukuphucula uphuhliso lwesisu

Iityuwa ze-butyrin acid ezisetyenziselwa ukuphucula ukusebenza kwezilwanyana ngeminyaka yoo-1990

Kwiminyaka yoo-2000> iityuwa ezigqunyiweyo zaphuhliswa: ukufumaneka ngcono kwamathumbu kunye nevumba elincinci

Ngowama-2010> Kuveliswa i-asidi entsha ye-butyric eqinisekisiweyo nesebenza kakuhle

Namhlanje imakethi ilawulwa yi-butyric acid ekhuselweyo kakuhle. Abavelisi bokutya abasebenza ngezi zongezo abanangxaki ngeengxaki zevumba kwaye impembelelo yezongezo kwimpilo yamathumbu kunye nokusebenza kakuhle ingcono. Ingxaki ngeemveliso eziqhelekileyo ezigqunywe nge-coated nangona kunjalo, uxinzelelo oluphantsi lwe-butyric acid. Iityuwa ezigqunywe nge-coated zihlala ziqulathe i-25-30% ye-butyric acid, esezantsi kakhulu.

Uphuhliso lwamva nje kwi-additives zokutya ezisekelwe kwi-butyric acid kukuphuhliswa kwe-ProPhorce™ SR: ii-glycerol esters ze-butyric acid. Ezi triglycerides ze-butyric acid zinokufumaneka ngokwemvelo kubisi nobusi. Zezona ziphambili kakhulu kwi-butyric acid ekhuselweyo kunye noxinzelelo lwe-butyric acid ukuya kuthi ga kwi-85%. I-Glycerol inendawo yokuba neemolekyuli ezintathu ze-butyric acid ezinamathele kuyo ngokusebenzisa oko kubizwa ngokuba yi-'ester bonds'. Olu nxibelelwano lunamandla lukhona kuzo zonke ii-triglycerides kwaye lunokuphulwa kuphela zii-enzymes ezithile (lipase). Kwisivuno nasesiswini i-tributyrin ihlala iqinile kwaye emathunjini apho i-pancreatic lipase ifumaneka khona ngokulula i-butyric acid iyakhutshwa.

Indlela yokwenza i-butyric acid ibe yi-esterifying iye yabonakala iyeyona ndlela isebenzayo yokwenza i-butyric acid engenavumba ekhutshwa apho uyifuna khona: emathunjini.

Umsebenzi weTributyrin

1.Ilungisa i-villi yamathumbu amancinci ezilwanyana kwaye ithintele iintsholongwane zamathumbu eziyingozi.

2.Iphucula ukufunxwa nokusetyenziswa kwezondlo.

3.Inganciphisa urhudo kunye noxinzelelo lokulunyulwa kwezilwanyana eziselula.

4.Iyandisa izinga lokusinda kunye nokwanda kobunzima bemihla ngemihla bezilwanyana eziselula.