I-Tributyrin iveliswa yinkampani i-Efine bIsekelwe kwiimpawu zomzimba kunye nolawulo lwesondlo kwitheknoloji ye-mucosa yamathumbu, uphando lohlobo olutsha lweemveliso zempilo yezilwanyana, lunokubuyisela ngokukhawuleza isondlo se-mucosa yamathumbu yezilwanyana, lukhuthaze uphuhliso kunye nokuvuthwa kwe-mucosa yamathumbu, lulungise zonke iintlobo zoxinzelelo olubangelwa kukonakala kwe-mucosa yamathumbu, lukhusele impilo yamathumbu, luqinise umsebenzi wokugaya kunye nokufunxwa kwamathumbu, lunokuthintela ngempumelelo i-necrotizing enteritis kwaye luphucule ukusebenza kwemveliso yemfuyo kunye neenkukhu.

Indlela yokusebenza kwe-butyric acid

Uninzi lwee-fatty acids ezifunekayo kwimfuyo nakwiinkukhu zinokufumaneka ekutyeni (ekutyeni), kodwa ezinye ii-fatty acids ezimfutshane (ezifana ne-butyric acid) azifumaneki ngokubanzi ekutyeni. Ii-fatty acids ezimfutshane, ingakumbi i-butyric acid, zidlala indima ebalulekileyo ekugcineni impilo yamathumbu emfuyo nakwiinkukhu, kuquka:

1.I-asidi ye-butyric ngumthombo wamandla okhawulezayo wokulungisa umonakalo wamathumbu emfuyo kunye neenkukhu, onokubola ngokukhawuleza kwaye ukhulule amandla, ukhuthaze ukukhula kwe-chorionic membrane, kwaye uphucule umsebenzi womqobo womzimba.

2.I-asidi ye-butyric inokunciphisa umxholo weoksijini emathunjini, ithintele ukuzala kweebhaktheriya eziyingozi ezitya ioksijini, kwaye ikhuthaze ukwanda kweebhaktheriya eziluncedo ezifana neebhaktheriya ze-lactic acid.

3. I-asidi ye-butyric ingenza kusebenze iimolekyuli zesignali ezisebenzayo zeeseli zomzimba zamathumbu kwaye iphucule ukhuseleko lwamathumbu kwi-mucosal.

Imithombo kunye nothelekiso lwe-butyric acid kwisondlo

Inkqubo ye-metabolic ye-butyric acid kwizilwanyana

Ukusebenza kakuhle kunye neempawu

1.Njengeyona fuel iphambili yokuphefumla kwiiseli ze-epithelial zamathumbu, inokubonelela ngamandla ngokukhawuleza kwiiseli ze-epithelial zamathumbu, ikhuthaze ngempumelelo ukukhula kweeseli ze-mucosal zamathumbu, ithathe inxaxheba ekugcinweni nasekulungisweni kwe-mucosal yamathumbu, kwaye igcine ukuthembeka nokusebenza kweeseli ze-mucosal zamathumbu.

2.Ukuphakama kwesisu samathumbu kwandisiwe,nciphile ubunzulu be-crypt , phuculaumlinganiselo wokuphakama kwe-intestinal villus ukuya kubunzulu be-crypt kunyephuculaisakhiwo sesimo samathumbu amancinci.

3.Yehlisa i-pH yamathumbu, ithintele ukukhula kweebhaktheriya ezibangela izifo ezifana ne-Escherichia coli, i-Salmonella kunye ne-Clostridium perfringens, ikhuthaza ukwanda kweebhaktheriya eziluncedo zebhaktheriya ye-lactic acid, ilawula ibhalansi ye-microecological yamathumbu emfuyo kunye neenkukhu.

4.Ukukhuthaza ukukhutshwa kwee-antibodies kunye nokwanda kweeseli zomzimba kwi-mucosa yamathumbu, ukuphucula amandla okulwa noxinzelelo kunye nokuzikhusela komzimba kwimfuyo nakwiinkukhu, ukunciphisa ukuvela kokudumba kwamathumbu kunye nezinye izifo..

Umfanekiso 1Iziphumo ze-triglyceride kunye ne-sodium butyrate ebotshelelweyo ekuzuzeni iinkukhu ezineentsiba ezimhlophe imihla ngemihla

Iziphumo zibonise ukuba xa kuthelekiswa neqela lolawulo, ukwanda kwemihla ngemihla kweenkukhu ezimhlophe ezineentsiba kunyuswe kakhulu ngokongezai-tributyrin, kwaye isiphumo sasingcono kuneso seqela le-sodium butyrate eligqunywe nge-coated

umfanekiso 2 Imiphumo ye-triglyceride kunye ne-sodium butyrate egqunywe yi-coated kwi-microflora yamathumbu eenkukhu ze-broilers

Iziphumo zibonise ukuba xa kuthelekiswa neqela lolawulo, zongezaI-Tributyrin inganciphisa kakhulu inani le-escherichia coli kwindlela yamathumbu eenkuku zenkukhu, kwaye yonyuse kakhulu inani leebhaktheriya ze-lactic acid, kwaye isiphumo sasingcono kuneso seqela le-sodium butyrate eligqunywe nge-coated.

Iziphumo ze-triglyceride kunye ne-sodium butyrate ekukhuleni kunye nesantya sorhudo lweHagu

Iziphumo zibonise ukuba, ngokufanayo neziphumo zee-antibiotics, i-triglyceride inokunyusa kakhulu ukwanda kwemihla ngemihla kwamantshontsho eehagu nge-11% ~ 14%, yehlise umlinganiselo wokutya kwenyama nge-0.13 ~ 0.15, kwaye yehlise kakhulu izinga lorhudo lwamantshontsho eehagu, nto leyo eyayingcono kakhulu kuneqela le-sodium butyrate.

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