I-Tributyrin isetyenziswa njengeSombululo sokuNcedisa ukutya okuSebenzayo. Yi-ester eyenziwe yi-butyric acid kunye ne-glycerol, eyenziwe ngokwenziwa kwe-butyric acid kunye ne-glycerol. Isetyenziswa kakhulu kwi-Feed Application. Ngaphandle kokusetyenziswa njengeSongezo sokuNcedisa ukutya kwiShishini leMfuyo, i-Tributyrin ikwayaziwa ngokusetyenziswa kwayo kwimveliso yeMargarine. I-Tributyrin ineenzuzo ezininzi ngokusetyenziswa njengeSombululo sokuSebenza kwizilwanyana nto leyo ekhokelela ekwandeni kwemveliso yokutya.

Iingenelo zempilo zeTributyrin
I-Tributyrin yi-precursor ye-butyric acid evumela iimolekyuli ezininzi ze-butyric acid ukuba zisiwe emathunjini amancinci ngokuthe ngqo ngenxa yendlela yokwenza i-esterification. Ngaloo ndlela, amazinga aphezulu kabini ukuya kathathu kuneemveliso eziqhelekileyo ezigqunywe nge-esterification. I-esterification ivumela iimolekyuli ezintathu ze-butyric acid ukuba zibotshelelwe kwi-glycerol enokwaphulwa kuphela yi-pancreatic lipase engapheliyo.

Xa iTributyrin ingena emathunjini ezilwanyana njengesongezelelo sokondla, inokukhutshwa kancinci kancinci iye kwi-butyric acid kunye ne-glycerol phantsi kwesenzo se-pancreatic lipase. ITributyrin inokulungisa i-villi yamathumbu amancinci ezilwanyana kwaye ithintele iintsholongwane eziyingozi emathunjini, nto leyo eyinzuzo enkulu kwishishini leeMfuyo. ITributyrin inokukhuthaza nokuphucula ukufunxwa nokusetyenziswa kwezondlo. Ikwanyusa izinga lokusinda kwaye ibangele ukwanda kobunzima bemihla ngemihla kwezilwanyana ezincinci.

Ukuze kongezwe i-butyric acid ekutyeni kweenkukhu, iityuwa ezinamafutha ze-sodium okanye i-calcium butyrate bezifumaneka kwimarike ukususela ngeminyaka yoo-1990 eziquka uqweqwe lwamafutha olufikelela kuma-70 ekhulwini lobunzima bemveliso iyonke. Uqweqwe lufihla ivumba elibi le-asidi ngandlela ithile; nangona kunjalo, abasebenzisi bokugqibela abafumani ixabiso elipheleleyo lotyalo-mali lwabo kuba umxholo we-butyric acid kwezi mveliso udla ngokuba phantsi.

I-TributyrinIngaqhekeka emzimbeni ukuze ivelise i-N-butyric acid enokunyusa ubude be-villi yamathumbu amancinci xa ifakwa ekutyeni kwehagu ekhulayo. I-Tributyrin ikwayi-glyceride ene-acid enamafutha aphantsi kwekhabhoni, efunxwa ngcono kune-glycerides ene-carbon chain fatty acid. Njengesongezelelo sokutya, inokukhuthaza kakhulu ukukhula kwemfuyo kunye neenkukhu kwaye iphucule ukusebenza kakuhle kokuguqulwa kokutya. I-Tributyrin ingasetyenziswa ngokubanzi njengabakhuthazi bokukhula ukususa iintsalela ze-antibiotic kwiimveliso zezilwanyana kunye nokuvelisa iimveliso zezilwanyana ezingenangcoliseko olusemgangathweni ophezulu.