I-Betainesisondlo esisebenzayo esisetyenziswa kakhulu njengesongezelelo sokondla izilwanyana, ikakhulu njengomnikeli we-methyl. I-betaine inokudlala yiphi indima ekutyeni kweenkukhu ezizalelayo kwaye zithini iziphumo?

Izaliswa kukutya okuvela kwizithako eziluhlaza. I-Betaine inokunikela ngokuthe ngqo kwelinye lamaqela ayo e-methyl kumjikelo we-methylation, ngelixa i-choline ifuna utshintsho lwe-enzyme olunezinyathelo ezimbini kwi-mitochondria ngaphakathi kweeseli zesibindi. Ke ngoko, i-betaine iya kusebenza ngakumbi njengomnikeli we-methyl xa kuthelekiswa ne-choline. Iimolekyuli ze-betaine ezongezelelweyo ziyakwazi ukungena kwiiseli ukugcina ukuthembeka kweeseli (zamathumbu), ulwakhiwo lweproteni, kunye ne-homeostasis. Ukugcina ukuthembeka kweeseli zamathumbu kunye nempilo yamathumbu sisiseko sokuphucula ukuphila, ukugaywa kwezakhamzimba kunye nemveliso.

Uvavanyo lwezorhwebo

Ukubonisa iziphumo ezilungileyo ze-betaine xa kuthelekiswa ne-choline, uphando lwezorhwebo lwase-US olwenziwe ngabasebenzi abadibeneyo lwenziwe ngexesha lemveliso yomaleko. Kwiiveki ezingama-21 ubudala, ii-Lohman brown layers kwinkqubo engenazikheyiji zanikwa ukutya okulawulayo okuquka i-500 ppm ye-60% ye-choline chloride okanye ukutya okuthathe indawo yale choline nge-348 ppm ye-Excential Beta-Key (betaine hydrochloride 95%). Kwi-348 ppm, ExcentialI-Beta-Keyithatha indawo ye-100% equimolar equivalence ye-500 ppm 60% choline chloride, oko kuthetha ukuba zombini ukutya kokulawula kunye nokuvavanya kunike inani elifanayo leemolekyuli zabaxhasi be-methyl, njenge-choline okanye i-betaine, ngokwahlukeneyo.

Idatha yemveliso ibonise ukuba xa inkukhu nganye ineeveki ezingama-59 ubudala okanye, kwiiveki ezingama-38 ukususela ekuqaleni kovavanyo, amaqanda aphakathi kwinkukhu nganye aphuculwe ngamaqanda angama-3.4. Ngokwembono yemveliso, amaqanda angama-60,396 angaphezulu avelisiweyo njengoko kubonwe kwiUmfanekiso 1.

Umfanekiso 1 – Ukuveliswa kwamaqanda aqokelelweyo ukususela kwiiveki ezingama-21-59 ubudala.

Ngaphandle kotshintsho kulawulo ngaphandle kokongeza i-betaine, kwimarike yaseMelika ukongezwa kwe-Excential Beta-Key kwi-348 ppm kunye nokutshintsha i-choline chloride eyongeziweyo kubalwe ukuba kubangele i-ROI ubuncinane eyi-6:1 kwimveliso yeentaka ezingama-20,000.

Impembelelo kumswakama kunye nokufa kwenkunkuma
Enye into ebalulekileyo ekulawuleni iinkukhu kukufuma kweenkuku. Ukucolwa kakuhle kwesisu kunye nokukhula kweeseli zamathumbu kuye kwanxulunyaniswa nokongezwa kwe-betaine. Ezi zinto zibangelwa kukugcinwa kwamanzi ngcono kwesilwanyana ngaloo ndlela kulawula indle.

Ukwanda komswakama wenkunkuma kunciphisa umgangatho wenkunkuma kwaye kunokukhokelela kwiingxaki zemveliso kuquka kodwa kungaphelelanga apho kumanqanaba aphezulu e-ammonia, ukwanda kweengxaki zomgangatho weenyawo kunye namaqanda angcolileyo. Ukuphucula ukugaywa kwezakhamzimba ngokongeza i-betaine nako kunokuchaphazela ukufuma kwenkunkuma. Ngexesha lovavanyo lorhwebo, iisampulu zenkunkuma kuzo zombini izindlu zaqokelelwa kwiiveki ezingama-35, 45 kunye nama-55. Nangona njengoko kubonwe kwiTheyibhile 1, ukufuma kwenkunkuma kwalawulwa kakuhle, ukongeza i-betaine hydrochloride kunciphisa kakhulu ukufuma ngaphezulu kwe-3%. Ukusebenzisa i-betaine hydrochloride endaweni ye-choline chloride, ingakumbi kwizindlu ezifuna ukulawula ukufuma kunokuba sisixhobo esiluncedo kubavelisi.

Ukufa kunye nokuhlala ixesha elide nazo ziimpawu ezibalulekileyo kumhlambi ophumelelayo. Njengoko kubonwe kwiTheyibhile 2, i-betaine inciphise ukufa komhlambi nge-1.98%.

I-Betaine sisixhobo esiluncedo kubavelisi

I-Excential Beta-Key ingathatha indawo ye-100% ye-choline chloride eyongeziweyo kwiileya. Ngenxa yokuba ukusebenza kakuhle kwe-betaine njenge-methyldonor kuphezulu xa kuthelekiswa ne-choline, intsalela ye-betaine ekhoyo kwiileya iphucula ukusebenza kakuhle kweseli kwaye inceda ukuphucula ukusebenza. Ngokunciphisa ukufa kunye nokufuma kwenkunkuma, i-betaine sisixhobo esiluncedo kubavelisi ukuphucula ukuphila kakuhle kweeleya. Ngokwandisa ukusebenza kakuhle kwe-osmoregulation, intsalela ye-betaine isenokunciphisa ukuwohloka kweproteni kwiqanda, ngoko ke i-betaine iphucula umgangatho weqanda kwaye yandisa ubutsha.