Ukusetyenziswa okunobuchule kwezongezo zesondlo esitsha-i-Glycerol Monolaurate kwi-aquaculture

Kwiminyaka yakutshanje, i-glycerides ye-MCFA, njengohlobo olutsha lwesongezo sokutya, ifumene ingqwalasela enkulu ngenxa yokusebenza kwayo okuphezulu kwe-antibacterial kunye nemiphumo enenzuzo kwimpilo yamathumbu.IGlycerol monolaurate (GML) sisondlo se-MCFA monoester ekhoyo kubisi lwebele kunye neoli yekhokhonathi. I-FDA ivumile ukuba ngokuqhelekileyo ithathwa njengekhuselekile xa isetyenziswe kuluhlu lwedosi ye-10 ukuya kwi-2000mg / kg kwiimveliso ezahlukeneyo. Ukongeza kwiimpembelelo zayo zokulwa ne-antibacterial kunye ne-antiviral, nayo ineempawu ze-emulsifying.

IGlycerol Monolaurate(CASNo:142-18-7）

 Igama:IGlycerol Monolaurate

Elinye igama:I-Monolaurin okanye i-GML

 Formula:C₁₅H₃₀O₄

ubunzima bemolekyuli:274.21

ukunyibilika:Inyibilika kancinane emanzinikunye ne-glycerol,Inyibilika kwi-methanol, i-ethano

Imbonakalo:Okuqinileyo okumhlophe okanye ukukhanya okutyheli

I-GML inamandla okuhlala kwindlela yokugaya ixesha elide kwaye iphucule amathumbu, oko kuthetha ukuba i-GML inokuchaphazela ngokuthe ngqo i-gut microbiome, inceda umzimba ukuba uvune izondlo ezingenakufunxwa kwaye ekugqibeleni zikhulise amandla omzimba wokufumana amandla.

Ukuza kuthi ga ngoku, iziphumo ezikhuthaza ukukhula kunye ne-immunomodulatory ye-monoglycerides kwiinkukhu ziye zaphononongwa ngokunzulu ukunyusa izinga lemveliso yeqanda, ukusebenza kakuhle kokutya, umgangatho weqanda elitsha kunye nexabiso lesondlo senkukhu. Ukongeza, i-GML nayo inefuthe lokukhuthaza impilo kunye nemisebenzi enamandla yokuchasana nokudumba kunye ne-antibacterial.

Iziphumo zesondlo se-monoglyceride ye-laurate (GML) ekusebenzeni kokukhula, i-enzymes yokugaya, ukubunjwa komzimba kunye nokuphendula okungabonakaliyo kwe-immune ye-Litopenaeus vannamei.

2. I-shrimp esetyenzisiweyo kwisifundo yondliwa ngokutya okune okuhlukeneyo, kunye ne-0, 350, 700 kunye ne-1050mg / kg ye-GML yongezwa kwisondlo ngokulandelanayo. Uvavanyo lwathatha iintsuku ezingama-60.

Iziphumo zophando zibonisa ukuba i-GML 700 kunye ne-1050 mg / kg iphucula kakhulu ukukhula komsebenzi, i-intestinal lipase kunye nemisebenzi ye-protease, ngelixa ukongezwa kwe-GML 1050 mg / kg ekudleni kwandisa i-serum lipids kunye ne-systemic crude lipids.

Imisebenzi ye-intestinal lipase kunye ne-protease ibonise ukunyuka okunyukayo kunye nokuguqulwa kwamanqanaba e-GML, kunye namaqela e-GML kwi-700 kunye ne-1050 mg / kg ye-dose amaqela aphezulu kakhulu kuneqela lokulawula (P <0.05). Okwangoku, amanqanaba ahlukeneyo e-GML ayengenayo impembelelo ebalulekileyo kumsebenzi wee-enzymes zokugaya kwi-hepatopancreas.

Ngaphezu koko, xa i-GML yongezwa kwisondlo kwi-concentrations ye-350 kunye ne-700mg / kg, iphakamisa ukukhuseleka kwe-shrimp ngokuphucula isimo sabo se-antioxidant kunye ne-antibacterial.

Amandla e-GML ephantsi njengesongezo sokutya ukuphucula ukukhula, umsebenzi we-enzyme yokugaya kunye nokungakhuseleki okuthe ngqo kwe-shrimp emhlophe. Ngokweziphumo zophando, ngenxa yemisebenzi eyandisiweyo ye-intestinal lipase kunye ne-protease, i-dose yokongeza i-700 kunye ne-1050 mg / kg ye-GML iphucule kakhulu ukusebenza kokukhula kwe-shrimp emhlophe evela eMzantsi Melika.