Ukutshintshwa okuncinci komgubo wentlanzi ngesidlo sesoya (i-SBM) njengendlela ezinzileyo neyoqoqosho kuye kwahlolwa kwiintlobo ngeentlobo zezilwanyana zasemanzini ezijoliswe kurhwebo, kuquka neentlanzi zasemanzini acocekileyo (i-freshwater rainbow trout).I-Oncorhynchus mykissNangona kunjalo, i-soy kunye nezinye izinto ezisekelwe kwizityalo ziqulathe amanqanaba aphezulu e-saponins kunye nezinye izinto ezichasene nesondlo ezibangela i-subacute enteritis yamathumbu akude kwiintlanzi ezininzi. Le meko ibonakaliswa kukwanda kokungena kwamathumbu, ukudumba, kunye nokungahambi kakuhle kwesimo somzimba okukhokelela ekunciphiseni ukusebenza kakuhle kokutya kunye nokukhula okungalunganga.

Kwi-rainbow trout, kuquka ne-SBM engaphezulu kwama-20% okutya kubonakalisiwe ukuba kubangela i-soy-enteritis, nto leyo ebeka umda womzimba kwinqanaba elinokutshintshwa kukutya okuqhelekileyo kwe-aquaculture. Uphando lwangaphambili luhlolisise iindlela ezininzi zokulwa nale enteritis, kubandakanya ukuphathwa kwe-microbiome yamathumbu, ukucubungula izithako ukususa izinto ezichasene nesondlo, kunye nezongezo ze-antioxidant kunye ne-probiotic. Enye indlela engahlolwanga kukufakwa kwe-trimethylamine oxide (TMAO) kwi-aquaculture feeds. I-TMAO yi-cytoprotective yendalo yonke, eqokelelwe kwiintlobo ezininzi njenge-protein kunye ne-membrane stabilizer. Apha, sivavanya amandla e-TMAO okuphucula uzinzo lwe-enterocyte kunye nokuthintela isignali ye-HSP70 yokuvuvukala ngaloo ndlela silwa ne-soy-induced enteritis kwaye ikhokelele ekwandeni kokusebenza kokutya, ukugcinwa kunye nokukhula kwi-freshwater rainbow trout. Ngaphaya koko, sihlola ukuba ingaba i-solubles yeentlanzi zaselwandle, umthombo otyebileyo we-TMAO, ingasetyenziswa njengendlela efanelekileyo yokulawula esi songezo, okwenza ukuba sisetyenziswe kwinqanaba lorhwebo.

Iintlanzi ze-rainbow trout ezifuywayo (i-Troutlodge Inc.) zazinobunzima obuphakathi be-40 g kunye ne-n = 15 ngetanki nganye kwiitanki zonyango eziphindwe kathathu. Iitanki zondliwa enye yezidlo ezintandathu ezilungiselelwe ngesiseko sesondlo esityiwayo esibonelela nge-40% yeproteni etyiwayo, i-15% yamafutha aluhlaza, kwaye zihlangabezana noxinzelelo olufanelekileyo lwe-amino acid. Ukutya kwakuquka i-fishmeal 40 control (% yokutya okomileyo), i-SBM 40, i-SBM 40 + i-TMAO 3 g kg.^-1, SBM 40 + TMAO 10 g kg^-1, SBM 40 + TMAO 30 g kg^-1, kunye ne-SBM 40 + 10% yezinto ezinyibilikayo kwiintlanzi. Amatanki atyiswa kabini ngemini ukuze abonakale ehluthi kangangeeveki ezili-12 kwaye kwenziwa uhlalutyo lwendle, olukufutshane, oluyi-histological kunye nolwe-molecular.

Iziphumo zolu phononongo ziza kuxutyushwa kunye nokubaluleka kokubandakanya iTMAO ukuze kuvumeleke ukusetyenziswa okuphezulu kweemveliso zesoya zase-US kwi-salmonid aquafeeds.