Igama:I-Tributyrin

Uvavanyo: 90%, 95%

Izithethantonye: I-glyceryl tributyrate               

Ifomula yeMolekyuli:C₁₅H₂₆O₆

Ubunzima beemolekyuli:302.3633

Inkangeleko: ulwelo lweoyile olutyheli ukuya kolungenambala, incasa ekrakra

Ifomula yemolekyuli ye-triglyceride tributyrate yi-C15H26O6, ubunzima bemolekyuli yi-302.37;

Njengomlandeli we-butyric acid, i-triglyceride luhlobo lwesongezelelo se-butyric acid esibalaseleyo esineempawu zomzimba nezekhemikhali ezizinzileyo, iziphumo ebezingalindelekanga nezikhuselekileyo. Ayisombululi nje kuphela ukusilela kwe-butyric acid enukayo neguquguqukayo, kodwa ikwasombulula ingxaki yokuba kunzima ukongeza i-butyric acid ngqo esiswini iye emathunjini, ngoko ke inokusetyenziswa ngokubanzi kwicandelo lesondlo sezilwanyana. Njengesongezelelo sokondla, i-triglyceride inokusebenza ngokuthe ngqo kwindlela yokugaya yezilwanyana, inike amandla kwindlela yokugaya yezilwanyana, iphucule impilo yamathumbu ezilwanyana, ilawule ukusebenza kokukhula kunye nemeko yempilo yezilwanyana.

Isiphumo seempawu:

1. 100% ngokusebenzisa isisu, akukho nkunkuma.

2. Nika amandla ngokukhawuleza: I-asidi ye-butyric kwimveliso iya kukhutshwa kancinci phantsi kwesenzo se-intestinal lipase, eyi-short chain fatty acid. Inika amandla kwi-intestinal mucosal cell ngokukhawuleza, ikhuthaza ukukhula ngokukhawuleza kunye nophuhliso lwe-intestinal mucosal.

3. Khusela i-mucosa yamathumbu: Uphuhliso kunye nokuvuthwa kwe-mucosa yamathumbu yeyona nto iphambili ekuthinteleni ukukhula kwezilwanyana ezincinci. Le mveliso ifunxwa kwiindawo zomthi we-foregut, i-midgut kunye ne-hindgut, ilungisa kwaye ikhusela ngempumelelo i-mucosa yamathumbu.

4. Ukubulala iintsholongwane: Ukuthintela urhudo olunesondlo oluvela kwi-colon segment kunye ne-ileitis, Ukwandisa ukumelana nezifo zezilwanyana, ukulwa noxinzelelo.

5. Khuthaza ubisi: Phucula ukutya kwabantwana abakhulelweyo. Khuthaza i-lactate yabantwana abakhulelweyo. Phucula umgangatho wobisi lwebele.

6. Ukukhula ngokuhambelanayo: Khuthaza ukutya kwamathole alumkileyo. Yandisa ukufunxwa kwezondlo, khusela amathole, nciphisa izinga lokufa.

7. Ukhuseleko ekusetyenzisweni: Phucula ukusebenza kwemveliso yezilwanyana. Yeyona succedaneum ilungileyo ye Antibiotic growth promoters.

8. Ixabiso liphezulu: Kukuphindwe kathathu ukonyusa ukusebenza kwe-butyric acid xa kuthelekiswa ne-Sodium butyrate.

Endaweni yokusebenzisa amayeza okubulala iintsholongwane

Okwangoku, zimbalwa iingxelo malunga nokutshintshwa kwee-antibiotics nge-triglyceride ekhaya nakwamanye amazwe.

Ukongezwa kwe-bacitracin zinc kunye needosi ezahlukeneyo zeTributyrin ekutyeni kwamantshontsho eehagu kubonise ukuba ukongezwa kwe-bacitracin zinc kwi-1 000 ukuya kwi-1 500 mg/kg kunokutshintsha ukongezwa kwee-antibiotics, kwaye kugcine ukusebenza kokukhula, imo yamathumbu kunye nokusebenza komzimba kwamantshontsho eehagu. Xa idosi yayiyi-2 000 ~ 2 500 mg/kg, yayingenakuthatha indawo yee-antibiotics kuphela, kodwa ikwaphucula kakhulu imo yamathumbu, ukusebenza kokukhula kunye nokuzikhusela kwamantshontsho eehagu, kwaye iphucule umgangatho wempilo yamantshontsho eehagu.

Kwiintsana ezilunyulweyo, ukutya okuphindwe kabini kongeza i-3 butyric acid glyceride kunye neoyile ye-oregano okanye i-salicylic acid methyl ester inokukhuthaza ixabiso le-V/C yamathumbu, iphucule imo yamathumbu eentsana ezilunyulweyo, inyuse kakhulu ubuninzi bocango oluqinileyo lwesikhunta sodonga, inciphise ukuguquka kweengcango, iibhaktheriya ze-defense coli, i-escherichia, ubuninzi, itshintshe isakhiwo sezityalo zamathumbu, kwaye i-metabolites inempilo yamathumbu eentsana ezilunyulweyo, Ingasetyenziswa kwiingulube ezilunyulweyo endaweni yee-antibiotics.

Ukutya okune-TB kunye nee-antibiotics kunokukhula okufanayo kwiihagu ezilunyulweyo, kwaye i-triglyceride kunye nee-antibiotics zinefuthe elifanelekileyo lokusebenzisana.